Acetamide
Based on 1 Customer Validation
Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 60-35-5
- Formula: C2H5NO
- Molecular Weight:59.07
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar (RccHan:WIST) rats and ICR (CD1) mice
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Dosage:250, 1000, 2000 mg/kg (acute exposure); 1000 mg/kg (subchronic assay)
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Administration:Oral gavage (p.o.), once daily for 2 consecutive days (acute exposure); Oral gavage (p.o.), once daily for 28 days (subchronic assay)
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Result:Did not induce micronucleated polychromatic erythrocytes (MN-PCE) in either mice or rats at acute (2 day) doses of 250, 1000, or 2000 mg/kg, or in rats following treatment with 1000 mg/kg/day for 28 days.
Chemical Information
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CAS No. 60-35-5
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Appearance Solid
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Molecular Weight 59.07
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Formula C2H5NO
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Color White to off-white
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SMILES
CC(N)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : 50 mg/mL (846.45 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (478 KB)
- English - EN (478 KB)
- Français - FR (478 KB)
- Deutsch - DE (478 KB)
- Norwegian - NO (478 KB)
- Español - ES (478 KB)
- Swedish - SV (478 KB)
- Italian - IT (478 KB)
- Korean - KR (478 KB)
- Portuguese - PT (478 KB)
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Handling Instructions (2659 KB)
References
[1]. Acetamide. IARC Monogr Eval Carcinog Risks Hum. 1999;71 Pt 3:1211-21. [Content Brief]
[2]. Moore MM, et, al. The food contaminant acetamide is not an in vivo clastogen, aneugen, or mutagen in rodent hematopoietic tissue. Regul Toxicol Pharmacol. 2019 Nov;108:104451. [Content Brief]
[3]. Autore G, et al. Acetamide derivatives with antioxidant activity and potential anti-inflammatory activity. Molecules. 2010 Mar 23;15(3):2028-38. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 16.9291 mL | 84.6453 mL | 169.2907 mL | 423.2267 mL |
| 5 mM | 3.3858 mL | 16.9291 mL | 33.8581 mL | 84.6453 mL | |
| 10 mM | 1.6929 mL | 8.4645 mL | 16.9291 mL | 42.3227 mL | |
| 15 mM | 1.1286 mL | 5.6430 mL | 11.2860 mL | 28.2151 mL | |
| 20 mM | 0.8465 mL | 4.2323 mL | 8.4645 mL | 21.1613 mL | |
| 25 mM | 0.6772 mL | 3.3858 mL | 6.7716 mL | 16.9291 mL | |
| 30 mM | 0.5643 mL | 2.8215 mL | 5.6430 mL | 14.1076 mL | |
| 40 mM | 0.4232 mL | 2.1161 mL | 4.2323 mL | 10.5807 mL | |
| 50 mM | 0.3386 mL | 1.6929 mL | 3.3858 mL | 8.4645 mL | |
| 60 mM | 0.2822 mL | 1.4108 mL | 2.8215 mL | 7.0538 mL | |
| 80 mM | 0.2116 mL | 1.0581 mL | 2.1161 mL | 5.2903 mL | |
| 100 mM | 0.1693 mL | 0.8465 mL | 1.6929 mL | 4.2323 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.