ALLO-647
ALLO-647 is a human monoclonal antibody targeting CD52. ALLO-647 transiently and selectively depletes host lymphocytes to promote the proliferation of allogeneic CAR T-cell following infusion. ALLO-647 can be used for the research of B-cell lymphoma and follicular lymphoma.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Human
ALLO-647 is a human monoclonal antibody targeting CD52, a GPI-anchored low-molecular-weight glycoprotein that is highly expressed on almost all mature T and B cells but not on hematopoietic stem cells. Soluble CD52 is a natural inhibitor of the NF‑κB pathway, which mainly functions in myeloid cells and also exerts cross-regulation in T/B cells.[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
CD52
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
Chemical Information
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ALLO-647 Related Classifications
HY-P992178 Related Classifications
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