BGC4
BGC4 is a biphenyl-based gold(III) complex. BGC4 inhibits human recombinant thioredoxin reductase (TrxR) with an IC50 of 10.7 μM, exhibits cytotoxicity (IC50 for MDA-MB-231 is 5.4 μM), and induces apoptosis. BGC4 exhibits antitumor efficacy in mouse models.
For research use only. We do not sell to patients.
- Formula: C30H33AuClF3N3
- Molecular Weight:725.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 725.02
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Formula C30H33AuClF3N3
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SMILES
CC(C)(C1=CC2=C(C=C1)C3=CC=C(C=C3[Au]2(C4N(C=CN4C5=NC=CC(C(F)(F)F)=C5)C)Cl)C(C)(C)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)