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Cat. No.: HY-123360

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BIBW 22

(Synonyms: BIBW22BS)

BIBW 22 (BIBW22BS) is a dipyridamole analogue. BIBW 22 is a potent bifunctional modulator that affects p-glycoprotein and nucleoside transport in tumor cells.

For research use only. We do not sell to patients.

CAS No.: 137694-16-7
Formula: C₃₀H₄₃N₇O₄
Molecular Weight:565.71

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

BIBW 22 Chemical Structure

CAS No.: 137694-16-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BIBW 22 (BIBW22BS) is a dipyridamole analogue. BIBW 22 is a potent bifunctional modulator that affects p-glycoprotein and nucleoside transport in tumor cells^[1].

Chemical Information

CAS No. 137694-16-7
Molecular Weight 565.71
Formula C₃₀H₄₃N₇O₄
SMILES

CC(C)(CN(CCO)C1=C2N=C(C(N3C[C@@H](O[C@@H](C3)C)C)=NC2=NC(N4C[C@@H](O[C@@H](C4)C)C)=N1)C5=CC=CC=C5)O
Synonyms

BIBW22BS
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen HX, et al. BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport. Cancer Res. 1993 May 1;53(9):1974-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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