EDANS
Based on 3 publication(s) in Google Scholar
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET).
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 50402-56-7
- Formula: C12H14N2O3S
- Molecular Weight:266.32
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) EDANS
More
Biological Activity
The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR[1].Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 50402-56-7
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Appearance Solid
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Molecular Weight 266.32
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Formula C12H14N2O3S
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Color Off-white to light yellow
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SMILES
O=S(C1=C2C=CC=C(NCCN)C2=CC=C1)(O)=O
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Synonyms
1,5-EDANS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (3)
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Journal Impact Factor
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Most Recent
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STAR Protoc
2023 May 5;4(2):102326. PMID: 37235475 -
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Solvent & Solubility
DMSO : 5.83 mg/mL (21.89 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7549 mL | 18.7744 mL | 37.5488 mL | 93.8720 mL |
| 5 mM | 0.7510 mL | 3.7549 mL | 7.5098 mL | 18.7744 mL | |
| 10 mM | 0.3755 mL | 1.8774 mL | 3.7549 mL | 9.3872 mL | |
| 15 mM | 0.2503 mL | 1.2516 mL | 2.5033 mL | 6.2581 mL | |
| 20 mM | 0.1877 mL | 0.9387 mL | 1.8774 mL | 4.6936 mL |
EDANS Related Classifications
HY-D1080 Related Classifications
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