Glenvastatin
Glenvastatin (HR 780) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Glenvastatin can reduces plasma total cholesterol and phospholipid levels and liver cholesterol contents. Glenvastatin does not increase the contents of cholesterol and total bile acid in the gallbladder bile. Glenvastatin can be used for the research of hyperlipemia
For research use only. We do not sell to patients.
- CAS No.: 122254-45-9
- Formula: C27H26FNO3
- Molecular Weight:431.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
5 nM
Compound: 2i
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Inhibition of cellular HMG-CoA reductase in cultures of human HEP G2 cells, determined by decreased incorporation of sodium [14C]acetate into cholesterol.
Inhibition of cellular HMG-CoA reductase in cultures of human HEP G2 cells, determined by decreased incorporation of sodium [14C]acetate into cholesterol.
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[PMID: 2296036] |
Chemical Information
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CAS No. 122254-45-9
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Molecular Weight 431.50
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Formula C27H26FNO3
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SMILES
O[C@@H](CC1=O)C[C@H](O1)/C=C/C2=C(C(C)C)N=C(C3=CC=CC=C3)C=C2C4=CC=C(F)C=C4
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Synonyms
HR 780
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glenvastatin Related Classifications
HY-106380 Related Classifications
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