Izonsteride
Izonsteride (Compound LY320236) is an inhibitor of 5α-reductase (IC50 = 11.6 nM for type I; 7.37 nM for type II). LY320236 inhibits the activity of steroid 5α-reductase, preventing the conversion of testosterone (T) to dihydrotestosterone (DHT). LY320236 can significantly inhibit the growth of LNCaP tumors in thymic mice without exhibiting obvious host toxicity.
For research use only. We do not sell to patients.
- CAS No.: 176975-26-1
- Formula: C24H26N2OS2
- Molecular Weight:422.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 176975-26-1
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Molecular Weight 422.61
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Formula C24H26N2OS2
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SMILES
C[C@@]12C3=CC=C(SC4=NC5=C(CC)C=CC=C5S4)C=C3CC[C@@]1([H])N(C(CC2)=O)C
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Synonyms
LY 320236
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Izonsteride Related Classifications
HY-106129 Related Classifications
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