NADase
Based on 1 Customer Validation
NADase is an ectoenzyme/membrane-bound enzyme targeting nicotinamide adenine dinucleotide (NAD+). NADase regulates intracellular NAD+ homeostasis by hydrolyzing NAD+ into nicotinamide mononucleotide (NMN) and ADP-ribose. NADase is promising for research of autoimmune diseases (e.g., systemic sclerosis, systemic lupus erythematosus) and aging-related disorders.
For research use only. We do not sell to patients.
- CAS No.: 9032-65-9
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Instructions
Dissolved in water (1 mg/mL) and diluted with 100 mM Potassium Phosphate Buffer (pH 7.3 at 37°C) before use. Fresh preparation is recommended.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
3.2.2.5
≥0.007 U/mg soild
One unit is defined as the amount of enzyme that will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37°C.
Chemical Information
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CAS No. 9032-65-9
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Appearance Solid
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Color Off-white to light yellow
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SMILES
[NADase]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)