delta-Valerobetaine

Name: delta-Valerobetaine
Brand: MedChemExpress
SKU: HY-114202
Rating: 4.5 (1 reviews)

Cat. No.: HY-114202 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO).

For research use only. We do not sell to patients.

delta-Valerobetaine Chemical Structure

CAS No. : 6778-33-2

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in Water ready for reconstitution	USD 265	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 265	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 620	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 920	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of delta-Valerobetaine:

delta-Valerobetaine-d₉ chloride Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO).

In Vitro

The levels of delta-valerobetaine were by far higher in ruminant than in non-ruminant meat and, among ruminants, cattle present higher levels of the substance than sheep and goat. The levels of delta-valerobetaine in milk of ruminants are much lower than in their meat. However, delta-valerobetaine content in milk of ruminants is noticeably higher than that observed in non-ruminant milk. It is showed that incubation of ruminal fluid with labeled N^ε-trimethyllysine leads to a rapid formation of labeled delta-valerobetaine^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

159.23

Formula

C₈H₁₇NO₂

CAS No.

6778-33-2

Appearance

Solid

Color

White to off-white

SMILES

C[N+](C)(C)CCCCC([O-])=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (785.03 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.2802 mL	31.4011 mL	62.8022 mL
5 mM	1.2560 mL	6.2802 mL	12.5604 mL
10 mM	0.6280 mL	3.1401 mL	6.2802 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (628.02 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (268 KB) SDS (0 KB)

COA (242 KB) HNMR (231 KB)

Handling Instructions (2659 KB)

References

[1]. Servillo L, et al. Ruminant meat and milk contain δ-valerobetaine, another precursor of trimethylamine N-oxide (TMAO) like γ-butyrobetaine. Food Chem. 2018 Sep 15;260:193-199. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.2802 mL	31.4011 mL	62.8022 mL	157.0056 mL
	5 mM	1.2560 mL	6.2802 mL	12.5604 mL	31.4011 mL
	10 mM	0.6280 mL	3.1401 mL	6.2802 mL	15.7006 mL
	15 mM	0.4187 mL	2.0934 mL	4.1868 mL	10.4670 mL
	20 mM	0.3140 mL	1.5701 mL	3.1401 mL	7.8503 mL
	25 mM	0.2512 mL	1.2560 mL	2.5121 mL	6.2802 mL
	30 mM	0.2093 mL	1.0467 mL	2.0934 mL	5.2335 mL
	40 mM	0.1570 mL	0.7850 mL	1.5701 mL	3.9251 mL
	50 mM	0.1256 mL	0.6280 mL	1.2560 mL	3.1401 mL
	60 mM	0.1047 mL	0.5234 mL	1.0467 mL	2.6168 mL
	80 mM	0.0785 mL	0.3925 mL	0.7850 mL	1.9626 mL
	100 mM	0.0628 mL	0.3140 mL	0.6280 mL	1.5701 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.