Demoxepam (Standard)
Demoxepam (Standard) is the analytical standard of Demoxepam. This product is intended for research and analytical applications. Demoxepam is a major metabolite of Chlordiazepoxide. Demoxepam exhibits cytotoxicity activity against cancer cell lines. Demoxepam has anticonvulsant and anxiolytic effects. Demoxepam has an inhibitory effect on in vitro [3H]tryptophan binding to rat hepatic nuclei.
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- CAS No.: 963-39-3
- Formule: C15H11ClN2O2
- Masse moléculaire:286.71
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 963-39-3
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Masse moléculaire 286.71
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Formule C15H11ClN2O2
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SMILES
O=C1NC2=CC=C(Cl)C=C2C(C3=CC=CC=C3)=[N+]([O-])C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Moustapha Ouédraogo, et al. In vitro cytotoxicity study of oxaziridines generated after chlordiazepoxide, demoxepam, and desmethylchlordiazepoxide UV irradiation. Drug Chem Toxicol. 2009;32(4):417-23. [Content Brief]
[2]. Gregory G Sarris, et al. Demoxepam Derivatization and GC-MS Analysis Produces Erroneous Nordiazepam and Oxazepam Results. J Anal Toxicol. 2019 Jun 1;43(5):406-410. [Content Brief]
[3]. Sidransky, H., et al., (1992). Inhibitory effect of demoxepam on tryptophan binding to rat hepatic nuclei. Biochemical medicine and metabolic biology, 47(3), 270–273. [Content Brief]
[4]. Vinkers, C. H., et al., (2010). The rapid hydrolysis of chlordiazepoxide to demoxepam may affect the outcome of chronic osmotic minipump studies. Psychopharmacology, 208(4), 555–562. . [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)