1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Digalacturonic acid

Digalacturonic acid is a metabolite of pectin or pectic acid. Digalacturonic acid can be used for the co-crystallization of enzymes such as proteinase K.

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Digalacturonic acid

Digalacturonic acid Chemical Structure

CAS No. : 5894-59-7

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Description

Digalacturonic acid is a metabolite of pectin or pectic acid. Digalacturonic acid can be used for the co-crystallization of enzymes such as proteinase K[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

370.26

Formula

C12H18O13

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C[C@H](O)[C@@H](O)[C@H]([C@H](O)C(O)=O)O[C@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)C(O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (135.04 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7008 mL 13.5040 mL 27.0080 mL
5 mM 0.5402 mL 2.7008 mL 5.4016 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.7008 mL 13.5040 mL 27.0080 mL 67.5201 mL
5 mM 0.5402 mL 2.7008 mL 5.4016 mL 13.5040 mL
10 mM 0.2701 mL 1.3504 mL 2.7008 mL 6.7520 mL
15 mM 0.1801 mL 0.9003 mL 1.8005 mL 4.5013 mL
20 mM 0.1350 mL 0.6752 mL 1.3504 mL 3.3760 mL
25 mM 0.1080 mL 0.5402 mL 1.0803 mL 2.7008 mL
30 mM 0.0900 mL 0.4501 mL 0.9003 mL 2.2507 mL
40 mM 0.0675 mL 0.3376 mL 0.6752 mL 1.6880 mL
50 mM 0.0540 mL 0.2701 mL 0.5402 mL 1.3504 mL
60 mM 0.0450 mL 0.2251 mL 0.4501 mL 1.1253 mL
80 mM 0.0338 mL 0.1688 mL 0.3376 mL 0.8440 mL
100 mM 0.0270 mL 0.1350 mL 0.2701 mL 0.6752 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Digalacturonic acid
Cat. No.:
HY-131591
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