NOTA-AE105
Based on 1 Customer Validation
NOTA-AE105 is a PET ligand for the urokinase-type plasminogen activator receptor (uPAR). NOTA-AE105 can be radiolabeled with 64Cu and 68Ga. Images of 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 demonstrate high contrast and clear tumor delineation. NOTA-AE105 can be used in the synthesis of radionuclide-conjugated compounds (RDCs).
For research use only. We do not sell to patients.
- Purity: 98.99%
- CAS No.: 1820563-84-5
- Formula: C72H102N16O20
- Molecular Weight:1511.68
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
Urokinase-type plasminogen activator receptor (uPAR)[2]
Chemical Information
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CAS No. 1820563-84-5
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Appearance Solid
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Molecular Weight 1511.68
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Formula C72H102N16O20
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
DMSO : 83.33 mg/mL (55.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6615 mL | 3.3076 mL | 6.6152 mL | 16.5379 mL |
| 5 mM | 0.1323 mL | 0.6615 mL | 1.3230 mL | 3.3076 mL | |
| 10 mM | 0.0662 mL | 0.3308 mL | 0.6615 mL | 1.6538 mL | |
| 15 mM | 0.0441 mL | 0.2205 mL | 0.4410 mL | 1.1025 mL | |
| 20 mM | 0.0331 mL | 0.1654 mL | 0.3308 mL | 0.8269 mL | |
| 25 mM | 0.0265 mL | 0.1323 mL | 0.2646 mL | 0.6615 mL | |
| 30 mM | 0.0221 mL | 0.1103 mL | 0.2205 mL | 0.5513 mL | |
| 40 mM | 0.0165 mL | 0.0827 mL | 0.1654 mL | 0.4134 mL | |
| 50 mM | 0.0132 mL | 0.0662 mL | 0.1323 mL | 0.3308 mL |