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RhoNox-1

45 Cited Publications
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Based on 45 publication(s) in Google Scholar

RhoNox-1 is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe2+. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm) . FeRhoNox-1 can enter the cell well, suitable for the detection of Fe2+ in living cells, and tends to be localized in the Golgi apparatus.

For research use only. We do not sell to patients.

  • Purity: 98.54%
  • CAS No.: 1447815-38-4
  • Formula: C28H30N2O4
  • Molecular Weight:458.55
  • Storage:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • RhoNox-1 Chemical Structure
    RhoNox-1 Chemical Structure
  • Experimental Validation Results for RhoNox-1
  • Experimental Validation Results for RhoNox-1
  • Experimental Validation Results for RhoNox-1
  • Experimental Validation Results for RhoNox-1
  • Experimental Validation Results for RhoNox-1
CAS No.: 1447815-38-4
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[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Flow Cytometry
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  • RhoNox-1 Chemical Structure
    RhoNox-1 Chemical Structure
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    RhoNox-1 purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Nov 5;23(1):703. [Abstract]

    Customer Validation
     RhoNox‐1 (1 µM; 30 min). Representative images of HK-2 cells stained with RhoNox-1 probe.

  • 1/16

    RhoNox-1 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Nov 10:e10991. [Abstract]

    Customer Validation
     RhoNox‐1 (10 µM; 30 min). The levels of Fe2+ in BMDMs were analyzed by immunostaining and flow cytometry analysis of FeRhoNox-1.

  • 1/16

    RhoNox-1 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 May 21:e2505359. [Abstract]

    Customer Validation
     Intracellular Fe2+ levels under 30 µM Erastin or 500 µM FAC (Ammonium iron(III) citrate) treatment for 4 h were detected with the RhoNox-1 (1μM; 1 h) fluorescent probe.

  • 1/16

    RhoNox-1 purchased from MedChemExpress. Usage Cited in: ACS Appl Mater Interfaces. 2025 Oct 22;17(42):57903-57918. [Abstract]

    Customer Validation
     RhoNox-1 (10 μM; 1 h). Fluorescence images showing intracellular Fe²⁺ (red; FeRhoNox-1) and nuclear staining (blue; Hoechst) in B16 cells after incubation with PFE-PEG NPs or PFE-PEG NPs plus NIR irradiation.

  • 1/16

    RhoNox-1 purchased from MedChemExpress. Usage Cited in: J Med Chem. 2025 Apr 24;68(8):8124-8142. [Abstract]

    Customer Validation
     RhoNox-1 (5 μM; 20 min). Flow cytometry analysis for intracellular Fe2+ levels (RhoNox-1) in U937 cell treated with DMSO or A9 for 48 h.

  • RhoNox-1