DL-Tartaric acid
Based on 1 publication(s) in Google Scholar
DL-Tartaric acid is an orally active and non-racemic mixture of L- and D-tartaric acid with antioxidant activity. 14C-labeled DL-Tartaric acid is nephrotoxic.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 133-37-9
- Formula: C4H6O6
- Molecular Weight:150.09
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) DL-Tartaric acid
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 133-37-9
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Appearance Solid
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Molecular Weight 150.09
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Formula C4H6O6
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Color White to yellow
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SMILES
O=C(O)[C@H](O)[C@@H](O)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 100 mg/mL (666.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (16.66 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (16.66 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
[1]. Down WH, et al. Renal and bone uptake of tartaric acid in rats: comparison of L(+) and DL-Forms. Toxicology. 1977 Dec;8(3):333-46. [Content Brief]
[2]. Mathias Ibert, et al. Determination of the side-products formed during the nitroxide-mediated bleach oxidation of glucose to glucaric acid. Carbohydr Res. 2002 Jun 5;337(11):1059-63. [Content Brief]
[3]. Thirada Piyanan, et al. An Instrument-free Detection of Antioxidant Activity Using Paper-based Analytical Devices Coated with Nanoceria. Anal Sci. 2018;34(1):97-102. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.6627 mL | 33.3133 mL | 66.6267 mL | 166.5667 mL |
| 5 mM | 1.3325 mL | 6.6627 mL | 13.3253 mL | 33.3133 mL | |
| 10 mM | 0.6663 mL | 3.3313 mL | 6.6627 mL | 16.6567 mL | |
| 15 mM | 0.4442 mL | 2.2209 mL | 4.4418 mL | 11.1044 mL | |
| 20 mM | 0.3331 mL | 1.6657 mL | 3.3313 mL | 8.3283 mL | |
| 25 mM | 0.2665 mL | 1.3325 mL | 2.6651 mL | 6.6627 mL | |
| 30 mM | 0.2221 mL | 1.1104 mL | 2.2209 mL | 5.5522 mL | |
| 40 mM | 0.1666 mL | 0.8328 mL | 1.6657 mL | 4.1642 mL | |
| 50 mM | 0.1333 mL | 0.6663 mL | 1.3325 mL | 3.3313 mL | |
| 60 mM | 0.1110 mL | 0.5552 mL | 1.1104 mL | 2.7761 mL | |
| 80 mM | 0.0833 mL | 0.4164 mL | 0.8328 mL | 2.0821 mL | |
| 100 mM | 0.0666 mL | 0.3331 mL | 0.6663 mL | 1.6657 mL |
DL-Tartaric acid Related Classifications
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