DMBA (Standard)
DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models.
For research use only. We do not sell to patients.
- CAS No.: 57-97-6
- Formula: C20H16
- Molecular Weight:256.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 57-97-6
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Molecular Weight 256.35
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Formula C20H16
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SMILES
CC(C1=CC=CC=C21)=C3C=CC4=CC=CC=C4C3=C2C
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Synonyms
7,12-DMBA (Standard); 7,12-Dimethylbenzanthracene (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Csiszar A, Balasubramanian P, Tarantini S, Yabluchanskiy A, Zhang XA, Springo Z, Benbrook D, Sonntag WE, Ungvari Z. Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 Apr;41(2):209-227. [Content Brief]
[2]. HUGGINS C, et al., Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression. Nature. 1961 Jan 21;189:204-7. [Content Brief]
[3]. Goerttler K, et al., Skin tumor formation in the European hamster (Cricetus cricetus L.) after topical initiation with 7,12-dimethylbenz[a]anthracene (DMBA) and promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA). Carcinogenesis. 1984 Apr;5(4):521-4. [Content Brief]
[4]. Saini RK, et al., Pulmonary carcinogenesis in mice with a single intratracheal instillation of 9, 10-dimethyl benz[a]anthracene. Drug Chem Toxicol. 2008;31(4):459-71. [Content Brief]
[5]. Gao J, et al., Microsomal expoxide hydrolase is required for 7,12-dimethylbenz[a]anthracene (DMBA)-induced immunotoxicity in mice. Toxicol Sci. 2007 Jul;98(1):137-44. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DMBA (Standard) Related Classifications
HY-W011845R Related Classifications
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