DPP-4-IN-18
DPP-4-IN-18 (Sitagliptin impurity 3) (Compound 4) impurity 3 is a potent, selective and orally active DPP-4 inhibitor with an IC50 of 27 nM. DPP-4-IN-18 can effectively prevent DPP-4 from degrading glucagon-like peptide 1 (GLP-1), thereby increasing the level of active GLP-1. DPP-4-IN-18 can be used for the research of type 2 diabetes.
For research use only. We do not sell to patients.
- CAS No.: 486460-31-5
- Formula: C16H16F5N5O
- Molecular Weight:389.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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DPP-4 27 nM (IC50) |
Chemical Information
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CAS No. 486460-31-5
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Molecular Weight 389.32
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Formula C16H16F5N5O
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SMILES
O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@H](N)CC3=CC(F)=CC=C3F
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Synonyms
Sitagliptin impurity 3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)