(E/Z)-Rivanicline
(E/Z)-Rivanicline ((E/Z)-RJR-2403, (E/Z)-Metanicotine) is the E/Z mixture of Rivanicline (HY-13225A). Rivanicline is a neuronal nicotinic receptor (neuronal nicotinic receptor) agonist that is highly selective for the α4β2 subtype, Ki is 26 nM, which is more than 1000 times more inhibitory than α7 receptor.
For research use only. We do not sell to patients.
- CAS No.: 538-79-4
- Formula: C10H14N2
- Molecular Weight:162.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PC-12 | EC50 |
>1 mM
Compound: 15
|
Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)
Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)
|
[PMID: 9435889] |
Chemical Information
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CAS No. 538-79-4
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Molecular Weight 162.23
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Formula C10H14N2
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SMILES
CNCC/C=C/C1=CC=CN=C1
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Synonyms
(E/Z)-RJR-2403; (E/Z)-Metanicotine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)