EGFR-IN-106
EGFR-IN-106 (compound 6) is a potent EGFR inhibitor with an IC50 value of 0.2396 μM. EGFR-IN-106 shows cytotoxic and anti-inflammatory activity.
For research use only. We do not sell to patients.
- Formula: C24H30N6O2
- Molecular Weight:434.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All EGFR Isoforms
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Biological Activity
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EGFR 0.2396 μM (IC50) |
EGFR-IN-106 (compound 6) (0-100 µM; 24 h) shows cytotoxic for AGS, A-431, MCF-7, MDA-MB-231, HaCaT cells with IC50s of 3.64, 0.034, 2.67, 10.51, >100 µM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:AGS, A-431, MCF-7, MDA-MB-231, HaCaT cells
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Concentration:0-100 µM
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Incubation Time:24 h
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Result:Inhibited cell viability with IC50s of 3.64, 0.034, 2.67, 10.51, >100 µM for AGS, A-431, MCF-7, MDA-MB-231, HaCaT cells, respectively.
Chemical Information
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Molecular Weight 434.53
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Formula C24H30N6O2
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SMILES
NC1=NC2=CC=C(NC(CCN)=O)C=C2C(NC([C@H](C3=CC=C(CC(C)C)C=C3)C)=O)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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