EGFR-IN-106
EGFR-IN-106 (compound 6) is a potent EGFR inhibitor with an IC50 value of 0.2396 μM. EGFR-IN-106 shows cytotoxic and anti-inflammatory activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C24H30N6O2
- Peso molecular:434.53
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
EGFR 0.2396 μM (IC50) |
In Vitro
EGFR-IN-106 (compound 6) (0-100 µM; 24 h) shows cytotoxic for AGS, A-431, MCF-7, MDA-MB-231, HaCaT cells with IC50s of 3.64, 0.034, 2.67, 10.51, >100 µM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:AGS, A-431, MCF-7, MDA-MB-231, HaCaT cells
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Concentration:0-100 µM
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Incubation Time:24 h
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Result:Inhibited cell viability with IC50s of 3.64, 0.034, 2.67, 10.51, >100 µM for AGS, A-431, MCF-7, MDA-MB-231, HaCaT cells, respectively.
Chemical Information
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Peso molecular 434.53
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Fòrmula C24H30N6O2
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SMILES
NC1=NC2=CC=C(NC(CCN)=O)C=C2C(NC([C@H](C3=CC=C(CC(C)C)C=C3)C)=O)=N1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR-IN-106 Related Classifications
HY-162323 Related Classifications
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