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Cat. No.: HY-158988

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EGFR-IN-114

EGFR-IN-114 (Compound 241) is a non-covalent, selective mutant EGFR inhibitor. EGFR-IN-114 is applicable to the research of non-small cell lung cancer.

For research use only. We do not sell to patients.

CAS No.: 2660252-31-1
Formula: C₃₀H₄₂FN₇O₃S
Molecular Weight:599.76

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

EGFR-IN-114 Chemical Structure

CAS No.: 2660252-31-1

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Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity

Description

EGFR-IN-114 (Compound 241) is a non-covalent, selective mutant EGFR inhibitor. EGFR-IN-114 is applicable to the research of non-small cell lung cancer^[1].

All EGFR Isoforms :

Chemical Information

CAS No. 2660252-31-1
Molecular Weight 599.76
Formula C₃₀H₄₂FN₇O₃S
SMILES

CC(C1=CC=C(N2[C@@H]([C@H](C2)CS(C)(=O)=O)C)C3=C1C=C(NC4=NC(N5C[C@](F)([C@@H](CC5)OCCN)C)=NC=C4)N=C3)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. John Emmerson Campbell, et al. Inhibitors of mutant forms of egfr. WO2021133809. 2022-06-23.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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EGFR-IN-114

All EGFR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

EGFR-IN-114 Related Classifications

HY-158988 Related Classifications