EGFR-IN-124
EGFR-IN-124 (compound 10A) is an EGFR inhibitor, with IC50 of 0.54 μM. EGFR-IN-124 can be used in anti-cancer research.
For research use only. We do not sell to patients.
- Formula: C34H22N6O
- Molecular Weight:530.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Description
IC50 & Target
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EGFR 0.54 μM (IC50) |
Chemical Information
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Molecular Weight 530.58
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Formula C34H22N6O
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SMILES
O=C1C2(C3=C(C=CC=C3)N1)C4=C(N(C5=CC=CC=C5)N=C4C6=CNC7=C6C=CC=C7)NC(C8=CC=CC=C8)=C2C#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)