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Cat. No.: HY-173501

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EGFR-IN-157

EGFR-IN-157 (compound IIB-5) is a potent EGFR inhibitor with an IC₅₀ of 18.81 nM. EGFR-IN-157 can be used in the study of non-small cell lung cancer (NSCLC).

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CAS No.: 3061364-63-1
Formule: C₂₈H₃₉N₉O₃S
Masse moléculaire:581.73

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

EGFR-IN-157 Chemical Structure

CAS No.: 3061364-63-1

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One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Activité biologique

Description

EGFR-IN-157 (compound IIB-5) is a potent EGFR inhibitor with an IC₅₀ of 18.81 nM. EGFR-IN-157 can be used in the study of non-small cell lung cancer (NSCLC)^[1].

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Chemical Information

CAS No. 3061364-63-1
Masse moléculaire 581.73
Formule C₂₈H₃₉N₉O₃S
SMILES

COC1=CC(N2CCC(N3CCN(C)CC3)CC2)=C(C)C=C1NC4=NC=CC(N5N=CC(NS(=O)(C6CC6)=O)=C5)=N4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wang H, et al. Design, synthesis, and biological evaluation of novel aminopyrimidine derivatives as EGFR inhibitors. Bioorg Med Chem Lett. 2025 Jul 1;122:130188. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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EGFR-IN-157

Voir tous les produits spécifiques à Isoform EGFR

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

EGFR-IN-157 Related Classifications

HY-173501 Related Classifications

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