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Cat. No.: HY-142681

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EGFR-IN-28

EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity.

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CAS No.: 2754392-31-7
Formule: C₃₁H₃₉BrN₁₀O₃S
Masse moléculaire:711.68

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

EGFR-IN-28 Chemical Structure

CAS No.: 2754392-31-7

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Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity^[1].

IC₅₀ & Target

^[1]

EGFR

Voir tous les produits spécifiques à Isoform EGFR :

In Vitro

EGFR-IN-28 inhibits Δ19Del, L858R, Δ19Del/T790M, L858R/T790M, Δ19Del/T790M/C797S, L858R/T790M/C797S (all IC₅₀s≤50nM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2754392-31-7
Masse moléculaire 711.68
Formule C₃₁H₃₉BrN₁₀O₃S
SMILES

CS(=O)(N(C1=C2N=CC=NC2=CC=C1NC3=NC(NC4=CC=C(N5CCC(N6CCN(C)CC6)CC5)C=C4OC)=NC=C3Br)C)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xianming Deng, et al. EGFR inhibitor, preparation method and application thereof. WO2021238827A1.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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EGFR-IN-28

Voir tous les produits spécifiques à Isoform EGFR

Activité biologique

Description

IC50 & Target

In Vitro

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

EGFR-IN-28 Related Classifications

HY-142681 Related Classifications

Bioz

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