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Referencia número: HY-143729

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EGFR-IN-29

EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2682200-93-5
Fòrmula: C₃₆H₄₆BrN₈O₂P
Peso molecular:733.68

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

EGFR-IN-29 Chemical Structure

No. CAS: 2682200-93-5

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Antibody-Drug Conjugates

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Bioz

Actividad biológica

Descripciòn

EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087^[1].

IC₅₀ & Target^[1]

EGFR^T790M

Ver todos los productos específicos de isoformas EGFR :

In Vitro

EGFR-IN-29 inhibits Ba/F3 cells with stable overexpression of △19del/T790M/C797S mutant genes, cells overexpressing EGFR WT and A431 carrying EGFR WT with IC₅₀ values of 6.8 nM, 151 nM and 1128 nM, respectively.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 2682200-93-5
Peso molecular 733.68
Fòrmula C₃₆H₄₆BrN₈O₂P
SMILES

O=P(C)(C)C1=C2C=CC(C3CC3)=NC2=CC=C1NC4=NC(NC5=C(OC)C=C(N6CCC(CC6)N7CCN(CC7)C)C(C)=C5)=NC=C4Br
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Xiangyong Liu. Quinolyl phosphine oxide compound, and composition and application thereof. Patent WO2021160087.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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EGFR-IN-29

Ver todos los productos específicos de isoformas EGFR

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

EGFR-IN-29 Related Classifications

HY-143729 Related Classifications