EGFR-IN-43
EGFR-IN-43 (Compound 17c) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-43 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-43 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-43 has superior anti-cancer activity.
For research use only. We do not sell to patients.
- CAS No.: 3031307-74-8
- Formula: C50H55ClFN5O5
- Molecular Weight:860.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Chemical Information
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CAS No. 3031307-74-8
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Molecular Weight 860.45
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Formula C50H55ClFN5O5
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SMILES
ClC1=CC(NC2=C3C(C=C(OC)C(OCCCNC(CCCCCCN(CCOC4=CC=C(C=C4)/C(C5=CC=C(C=C5)O)=C(CC)\C6=CC=CC=C6)C)=O)=C3)=NC=N2)=CC=C1F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)