EGFR-IN-67
EGFR-IN-67 (Compound 7d) is a potent EGFR inhibitor with an IC50 of 0.34 μM. EGFR-IN-67 shows anticancer activity.
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- No. CAS: 2416924-99-5
- Fòrmula: C18H17N3S
- Peso molecular:307.41
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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EGFR 0.34 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
4.53 μM
Compound: 26a
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 39106658] |
EGFR-IN-67 (Compound 7d) shows cytotoxicity with IC50 values of 4.53 ± 0.28 μM and 39.10 ± 2.37 μM against MCF-7 and WI-38, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2416924-99-5
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Peso molecular 307.41
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Fòrmula C18H17N3S
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SMILES
S=C(N1N=C(C2=CC=CC=C2)CC1/C=C/C3=CC=CC=C3)N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)