EGFR-IN-67
EGFR-IN-67 (Compound 7d) is a potent EGFR inhibitor with an IC50 of 0.34 μM. EGFR-IN-67 shows anticancer activity.
For research use only. We do not sell to patients.
- CAS No.: 2416924-99-5
- Formula: C18H17N3S
- Molecular Weight:307.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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EGFR 0.34 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
4.53 μM
Compound: 26a
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Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 39106658] |
EGFR-IN-67 (Compound 7d) shows cytotoxicity with IC50 values of 4.53 ± 0.28 μM and 39.10 ± 2.37 μM against MCF-7 and WI-38, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2416924-99-5
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Molecular Weight 307.41
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Formula C18H17N3S
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SMILES
S=C(N1N=C(C2=CC=CC=C2)CC1/C=C/C3=CC=CC=C3)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR-IN-67 Related Classifications
HY-147996 Related Classifications
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