EGFR-IN-75
EGFR-IN-75 is an EGFRWT and EGFRT790M inhibitor with IC50 values of 0.28 μM and 5.02 μM, respectively. EGFR-IN-75 shows anticancer and antioxidant activity.
For research use only. We do not sell to patients.
- Formula: C10H6N6S2
- Molecular Weight:274.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All EGFR Isoforms
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Biological Activity
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EGFRWT 0.28 μM (IC50) |
EGFRT790M 5.02 μM (IC50) |
EGFR-IN-75 (compound 2) shows cytotoxicity against MCF-7 and A549 cell lines with IC50 values of 4.92 μM and 4.69 μM, respectively[1].
EGFR-IN-75 (compound 2) also has the best antioxidant property, decreasing the radical scavenging activity by 78%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 274.32
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Formula C10H6N6S2
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SMILES
NC1=NC=NC2=C1SC3=C2C4=C(C(N)=NC=N4)S3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR-IN-75 Related Classifications
HY-152144 Related Classifications
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