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Art. -Nr.: HY-N21588

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Eleocharin A

Eleocharin A is an isoprenylated flavonoid compound found in the pericarp of Eleocharis tuberosa and the twigs of Artocarpus nigrifolius. Eleocharin A exhibits DPPH radical scavenging activity and reducing power antioxidant activity. Eleocharin A exerts cytotoxic effects on cancer cells. Eleocharin A can be used in research on cervical cancer and gastric cancer.

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CAS. Nr.: 1619976-96-3
Formel: C₂₀H₁₆O₆
Molecular Weight:352.34

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Eleocharin A Chemical Structure

CAS. Nr.: 1619976-96-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
SiHa	IC50	0.7 μM	Antiproliferative activity against human cervical cancer SiHa cells incubated for 48 h assessed by MTT assay. Antiproliferative activity against human cervical cancer SiHa cells incubated for 48 h assessed by MTT assay.	29607909
SGC-7901	IC50	8.3 μM	Antiproliferative activity against human gastric cancer SGC-7901 cells incubated for 48 h assessed by MTT assay. Antiproliferative activity against human gastric cancer SGC-7901 cells incubated for 48 h assessed by MTT assay.	29607909

In Vitro

Eleocharin A (compound 10) (100-5000 μg/L; 48 h) effectively inhibits the proliferation of SiHa human cervical cancer cells (IC₅₀ = 0.7 μM) and SGC-7901 human gastric cancer cells (IC₅₀ = 8.3 μM) in vitro^[1].
Eleocharin A (compound 1) (0.05-16 mg/mL; 30 min) exhibits strong DPPH radical scavenging activity in cell-free antioxidant assays^[2].
Eleocharin A (0.1 mg/mL; 20 min) exhibits iron-reducing capacity in cell-free assays^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

human cervical cancer SiHa cells, human gastric cancer SGC-7901 cells
Concentration:

100, 1000, 2000, 5000 μg/L
Incubation Time:

48 h
Result:

Exhibited significant cytotoxicity against SiHa human cervical cancer cells with an IC₅₀ of 0.7 μM.
Exhibited inhibitory activity against SGC-7901 human gastric cancer cells with an IC₅₀ of 8.3 μM.

Chemical Information

CAS. Nr. 1619976-96-3
Molecular Weight 352.34
Formel C₂₀H₁₆O₆
SMILES

O=C1C=C(C2=CC(O)=C(O)C=C2)OC3=CC4=C(C(O)=C13)C=CC(C)(C)O4
Structure Classification
- Flavonoids
- Flavonols
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Liu X, et al. Prenylflavonoids from the Twigs of Artocarpus nigrifolius. Chemical & pharmaceutical bulletin. 2018;66(4):434-438.

[2]. Luo Y, et al. Isolation, characterisation, and antioxidant activities of flavonoids from chufa (Eleocharis tuberosa) peels. Food chemistry. 2014 Dec 01;164:30-5.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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