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Elgemtumab

(Synonyms: LJM716)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Elgemtumab(LJM716) is a fully human IgG monoclonal antibody. Elgemtumab can specifically bind to HER3, block ligand-dependent and independent HER3 signal transduction and cell proliferation, and has good anti-tumor potential.

For research use only. We do not sell to patients.

  • Purity: 99.00%
  • CAS No.: 1512559-37-3
  • Molecular Weight:143.977 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Elgemtumab
  • Experimental Validation Results for Elgemtumab
  • Experimental Validation Results for Elgemtumab
  • Elgemtumab Chemical Structure
    Elgemtumab Chemical Structure
CAS No.: 1512559-37-3
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometric analysis of 1X106 MCF-7 cells labeling Elgemtumab (HY-P99936, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Loaded Elgemtumab on AHC2 biosensor, can bind HER3 Protein, Human (HEK293, His, solution, HY-P72625A) with an affinity constant of <1.000E-11 M as determined in BLI assay.

  • Elgemtumab Chemical Structure
    1/16
  • Elgemtumab
  • Flow cytometric analysis of 1X106 MCF-7 cells labeling Elgemtumab (HY-P99936, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Loaded Elgemtumab on AHC2 biosensor, can bind HER3 Protein, Human (HEK293, His, solution, HY-P72625A) with an affinity constant of <1.000E-11 M as determined in BLI assay.