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Cat. No.: HY-10315

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Elarofiban

(Synonyms: RWJ-53308)

Elarofiban (RWJ-53308) is a nonpeptide, orally active antagonist for fibrinogen receptor α_IIbβ₃ (GPIIb/IIIa), with an IC₅₀ of 0.15 nM. Elarofiban has the potential for platelet mediated thrombotic disorders research.

For research use only. We do not sell to patients.

CAS No.: 198958-88-2
Formula: C₂₂H₃₂N₄O₄
Molecular Weight:416.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Elarofiban Chemical Structure

CAS No.: 198958-88-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Integrin Isoforms :

Chemical Information

CAS No. 198958-88-2
Molecular Weight 416.51
Formula C₂₂H₃₂N₄O₄
SMILES

O=C(N[C@H](C1=CN=CC=C1)CC(O)=O)[C@H]2CN(CCC2)C(CCC3CCNCC3)=O
Synonyms

RWJ-53308
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Judith H. Cohen, et al. A Practical Synthesis of the Platelet Fibrinogen Antagonist, Elarofiban. Organic Process Research & Development 2003, 7, 866-872.

[2]. De Corte BL, et al., Piperidine-containing beta-arylpropionic acids as potent antagonists of alphavbeta3/alphavbeta5 integrins. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5227-32. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Elarofiban

All Integrin Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Elarofiban Related Classifications

HY-10315 Related Classifications