GPS491
GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.
For research use only. We do not sell to patients.
- CAS No.: 2655502-29-5
- Formula: C13H5F6N3OS2
- Molecular Weight:397.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | CC50 |
2.51 μM
Compound: 29; GPS491
|
Cytotoxicity against human PBMC cells assessed as cell viability measured after 11 days by Viacount assay
Cytotoxicity against human PBMC cells assessed as cell viability measured after 11 days by Viacount assay
|
[PMID: 34795872] |
Chemical Information
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CAS No. 2655502-29-5
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Molecular Weight 397.32
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Formula C13H5F6N3OS2
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SMILES
O=C(NC1=NC(C=CC(C(F)(F)F)=C2)=C2S1)C3=CN=C(C(F)(F)F)S3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)