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Referencia número: HY-U00072

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RS-601

Name: RS-601
Brand: MedChemExpress
SKU: HY-U00072
Price: 1347.00 USD
Availability: InStock
Rating: 5 (1 reviews)

RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.

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No. CAS: 207987-59-5
Fòrmula: C₂₂H₂₃F₆NO₄S
Peso molecular:511.48

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

RS-601 Chemical Structure

No. CAS: 207987-59-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.

IC₅₀ & Target^[1]

LTD₄	TXA₂ Receptor

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In Vivo

RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4 in a dose-dependent fashion in guinea pigs. RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction, respectively. RS-601 significantly inhibits the late-phase response and LPS-induced AHR at a dose of 10 mg/kg, but does not affect biphasic bronchial responses. RS-601 (3 and 10 mg/kg) also clearly inhibits the AHR^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 207987-59-5
Peso molecular 511.48
Fòrmula C₂₂H₂₃F₆NO₄S
SMILES

O=C(O)CCCC1=CC=C(C(NS(=O)(C2=CC=C(F)C=C2)=O)CCCC(F)(F)C(F)(F)F)C=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Yamada T, et al. Effects of RS-601, a novel leukotriene D(4)/thromboxane A(2) dual receptor antagonist, on asthmatic responses in guinea pigs. Pharmacology. 2003 Sep;69(1):51-8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RS-601

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Montelukast sodium

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LY255283

Masilukast

YM158 free base

SR2640 hydrochloride

ONO4057

Ablukast

Bunaprolast

Etalocib (Standard)

Montelukast sodium (Standard)

Ver todos los productos específicos de isoformas Leukotriene Receptor

Ver todos los productos específicos de isoformas Prostaglandin Receptor

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

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Bioz

RS-601

KP496

Montelukast sodium

Etalocib

LY255283

Masilukast

YM158 free base

SR2640 hydrochloride

ONO4057

Ablukast

Bunaprolast

Etalocib (Standard)

Montelukast sodium (Standard)

Ver todos los productos específicos de isoformas Leukotriene Receptor

Ver todos los productos específicos de isoformas Prostaglandin Receptor

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

RS-601 Related Classifications

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