country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-N21588

Copy Link Print Information

Eleocharin A

Eleocharin A is an isoprenylated flavonoid compound found in the pericarp of Eleocharis tuberosa and the twigs of Artocarpus nigrifolius. Eleocharin A exhibits DPPH radical scavenging activity and reducing power antioxidant activity. Eleocharin A exerts cytotoxic effects on cancer cells. Eleocharin A can be used in research on cervical cancer and gastric cancer.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1619976-96-3
Fòrmula: C₂₀H₁₆O₆
Peso molecular:352.34

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Eleocharin A Chemical Structure

No. CAS: 1619976-96-3

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
SiHa	IC50	0.7 μM	Antiproliferative activity against human cervical cancer SiHa cells incubated for 48 h assessed by MTT assay. Antiproliferative activity against human cervical cancer SiHa cells incubated for 48 h assessed by MTT assay.	29607909
SGC-7901	IC50	8.3 μM	Antiproliferative activity against human gastric cancer SGC-7901 cells incubated for 48 h assessed by MTT assay. Antiproliferative activity against human gastric cancer SGC-7901 cells incubated for 48 h assessed by MTT assay.	29607909

In Vitro

Anti-cancerOxidative Stress

Anti-cancer

Eleocharin A (compound 10) (100-5000 μg/L; 48 h) effectively inhibits the proliferation of SiHa human cervical cancer cells (IC₅₀ = 0.7 μM) and SGC-7901 human gastric cancer cells (IC₅₀ = 8.3 μM) in vitro^[1].

Oxidative Stress

Eleocharin A (compound 1) (0.05-16 mg/mL; 30 min) exhibits strong DPPH radical scavenging activity in cell-free antioxidant assays^[2].
Eleocharin A (0.1 mg/mL; 20 min) exhibits iron-reducing capacity in cell-free assays^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

human cervical cancer SiHa cells, human gastric cancer SGC-7901 cells
Concentration:

100, 1000, 2000, 5000 μg/L
Incubation Time:

48 h
Result:

Exhibited significant cytotoxicity against SiHa human cervical cancer cells with an IC₅₀ of 0.7 μM.
Exhibited inhibitory activity against SGC-7901 human gastric cancer cells with an IC₅₀ of 8.3 μM.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

Chemical Information

No. CAS 1619976-96-3
Peso molecular 352.34
Fòrmula C₂₀H₁₆O₆
SMILES

O=C1C=C(C2=CC(O)=C(O)C=C2)OC3=CC4=C(C(O)=C13)C=CC(C)(C)O4
Structure Classification
- Flavonoids
- Flavonols
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Liu X, et al. Prenylflavonoids from the Twigs of Artocarpus nigrifolius. Chemical & pharmaceutical bulletin. 2018;66(4):434-438.

[2]. Luo Y, et al. Isolation, characterisation, and antioxidant activities of flavonoids from chufa (Eleocharis tuberosa) peels. Food chemistry. 2014 Dec 01;164:30-5.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto