Copy Link Print Information

Modakafusp alfa

(Synonyms: TAK-573)
Revisión del cliente

Based on 1 Customer Validation

Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 96.22%
  • No. CAS: 2254522-19-3
  • Peso molecular:183.48 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Modakafusp alfa
  • Experimental Validation Results for Modakafusp alfa
  • Experimental Validation Results for Modakafusp alfa
  • Modakafusp alfa Chemical Structure
    Modakafusp alfa Chemical Structure
No. CAS: 2254522-19-3
Tamaño
Precio
Stock
Cantidad
Amount: USD 0.00
Please select quantity
or
or

* Seleccione Cantidad antes de agregar artículos.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Modakafusp alfa Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
  • Actividad biológica
  • Chemical Information
  • Pureza y Documentación
  • Referencias
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
MOQ
Minimum order quantity
100 mg

Obtener un presupuesto En stock

Other size
Obtener un presupuesto
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Inicie sesiòn
Registrar
Sign in to MedChemExpress
Registrar una cuenta nueva

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Modakafusp alfa can bind Human CD38 Protein (ECD, His Tag). The EC50 for this effect is 2.553 ng/mL.

  • 1/16

    Immobilized Modakafusp alfa can bind Anti-Interferon alpha 2/IFNA2 Antibody. The EC50 for this effect is 14.45 ng/mL.

  • Modakafusp alfa Chemical Structure
    1/16
  • Modakafusp alfa
  • Immobilized Modakafusp alfa can bind Human CD38 Protein (ECD, His Tag). The EC50 for this effect is 2.553 ng/mL.
  • Immobilized Modakafusp alfa can bind Anti-Interferon alpha 2/IFNA2 Antibody. The EC50 for this effect is 14.45 ng/mL.