RDEA-427
RDEA-427 is a pyrrolopyrimidine derivative and also a HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). RDEA-427 acts on wild-type and NNRTI-resistant mutant HIV-1. RDEA-427 can be used in research related to HIV infection.
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- No. CAS: 914496-19-8
- Fòrmula: C22H16N6O
- Peso molecular:380.41
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
HIV-1 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | EC50 |
0.9 nM
Compound: RDEA427
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Antiviral activity against HIV1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect after 5 days by MTT assay
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect after 5 days by MTT assay
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[PMID: 25707013] |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 914496-19-8
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Peso molecular 380.41
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Fòrmula C22H16N6O
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SMILES
N#CC1=CC=C(C=C1)NC=2N=C(OC=3C(=CC(C#N)=CC3C)C)C=4C=CNC4N2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RDEA-427 Related Classifications
HY-111147 Related Classifications
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