Tipifarnib (Standard)
Tipifarnib (Standard) is the analytical standard of Tipifarnib (HY-10502). This product is intended for research and analytical applications. Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC50 of 0.86 nM. Antineoplastic activity and antiparasitic activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 95%
- No. CAS: 192185-72-1
- Fòrmula: C27H22Cl2N4O
- Peso molecular:489.40
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-10502
TipifarnibFTase Inhibitor -
HY-15136
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HY-50876
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HY-10038
A 922500DGAT-1 Inhibitor -
HY-16273A
L-778123 hydrochlorideFarnesyl Transferase Inhibitor -
HY-17406
TolcaponeCOMT Inhibitor -
HY-N6796
Manumycin AAntibiotic, TrxR-1 Inhibitor -
HY-15879
LB42708Farnesyltransferase Inhibitor -
HY-108467
GGsTopγ GGT Inhibitor -
HY-16373
CP-609754Farnesyltransferase Inhibitor -
HY-16273
L-778123FPTase/GGPTase-I Iinhibitor
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 192185-72-1
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Peso molecular 489.40
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Fòrmula C27H22Cl2N4O
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SMILES
O=C1N(C2=C(C(C3=CC=CC(Cl)=C3)=C1)C=C(C=C2)[C@@](N)(C4=CN=CN4C)C5=CC=C(C=C5)Cl)C
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Synonyms
IND 58359 (Standard); R115777 (Standard)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Devendra S Puntambekar, et al. Inhibition of farnesyltransferase: a rational approach to treat cancer? J Enzyme Inhib Med Chem. 2007 Apr;22(2):127-40. [Content Brief]
[2]. End DW, et al. Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro. Cancer Res. 2001 Jan 1;61(1):131-7 [Content Brief]
[3]. Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8(1):8161. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tipifarnib (Standard) Related Classifications
HY-10502R Related Classifications
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