Fasoracetam (Standard)
Fasoracetam (NS 105) Standard is the analytical standard of Fasoracetam (HY-107481). This product is intended for research and analytical applications. Fasoracetam (NS105) is an orally active metabotropic glutamate receptor (mGluR) activator. Fasoracetam bidirectionally regulates adenylyl cyclase activity and cAMP levels by activating group I-III mGluRs, upregulating GABAB receptors, and enhancing cholinergic neurotransmission. Fasoracetam can be used in research on attention deficit hyperactivity disorder (ADHD), depression, dementia, Alzheimer's disease, and forebrain ischemia.
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- Pureté : 98%
- CAS No.: 110958-19-5
- Formule: C10H16N2O2
- Masse moléculaire:196.25
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 110958-19-5
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Masse moléculaire 196.25
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Formule C10H16N2O2
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SMILES
O=C([C@@H]1NC(CC1)=O)N2CCCCC2
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Synonyms
NS 105 (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Elia J, et al. Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling. Nature communications. 2018 Jan 16;9(1):4. [Content Brief]
[2]. Hirouchi M, et al. Role of metabotropic glutamate receptor subclasses in modulation of adenylyl cyclase activity by a nootropic NS-105. European journal of pharmacology. 2000 Jan 03;387(1):9-17. [Content Brief]
[4]. Ogasawara T, et al. Involvement of cholinergic and GABAergic systems in the reversal of memory disruption by NS-105, a cognition enhancer. Pharmacology, biochemistry, and behavior. 1999 Sep;64(1):41-52. [Content Brief]
[5]. Shorvon S. Pyrrolidone derivatives. The Lancet. 2001 Dec 1;358(9296):1885-92. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)