Fipexide hydrochloride

Name: Fipexide hydrochloride
Brand: MedChemExpress
SKU: HY-B1124A
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1124A Purity: 99.88%: FAQs
Data Sheet SDS COA Handling Instructions

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Fipexide hydrochloride, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide hydrochloride reduces striatal adenylate cyclase activity. Fipexide hydrochloride has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. Fipexide hydrochloride acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection.

For research use only. We do not sell to patients.

Fipexide hydrochloride Chemical Structure

CAS No. : 34161-23-4

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25 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 75	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Fipexide hydrochloride:

Fipexide In-stock

1 Publications Citing Use of MCE Fipexide hydrochloride

•Int J Mol Med. 2019 Oct 31;20(21):5448. [Abstract]

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Fipexide (50 μM; for 15 days) hydrochloride shows simple structures, which contained epidermal regions with well-expanded cells and actively dividing regions for Arabidopsis wild-type seedlings^[2]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Fipexide (10 mg/kg; orally; 5-10 days) hydrochloride completely abolishes the memory deficit produced by kindling in rats^[3]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Kindled rats^[3]
Dosage:	10 mg/kg
Administration:	Orally; 5-10 days
Result:	Completely abolishes the memory deficit produced by kindling. Antagonized the amnestic effect of Pentylenetetrazole (PTZ) -kindling.

Molecular Weight

425.31

Formula

C₂₀H₂₂Cl₂N₂O₄

CAS No.

34161-23-4

Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(OCC(N2CCN(CC3=CC=C(OCO4)C4=C3)CC2)=O)C=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (117.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3512 mL	11.7561 mL	23.5123 mL
5 mM	0.4702 mL	2.3512 mL	4.7025 mL
10 mM	0.2351 mL	1.1756 mL	2.3512 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.88%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (245 KB) LCMS (106 KB)

Handling Instructions (2659 KB)

References

[1]. A Marino, et al. Fipexide improvement of cognitive functions in rat: behavioural and neurochemical studies. Pharmacol Res. Mar-Apr 1990;22(2):179-87. [Content Brief]

[2]. Takeshi Nakano, et al.FPX is a Novel Chemical Inducer that Promotes Callus Formation and Shoot Regeneration in Plants. Plant Cell Physiol. 2018 Aug 1;59(8):1555-1567. [Content Brief]

[3]. M G Genkova-Papazova, et al. Piracetam and fipexide prevent PTZ-kindling-provoked amnesia in rats. Eur Neuropsychopharmacol. 1996 Nov;6(4):285-90. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.3512 mL	11.7561 mL	23.5123 mL	58.7807 mL
	5 mM	0.4702 mL	2.3512 mL	4.7025 mL	11.7561 mL
	10 mM	0.2351 mL	1.1756 mL	2.3512 mL	5.8781 mL
	15 mM	0.1567 mL	0.7837 mL	1.5675 mL	3.9187 mL
	20 mM	0.1176 mL	0.5878 mL	1.1756 mL	2.9390 mL
	25 mM	0.0940 mL	0.4702 mL	0.9405 mL	2.3512 mL
	30 mM	0.0784 mL	0.3919 mL	0.7837 mL	1.9594 mL
	40 mM	0.0588 mL	0.2939 mL	0.5878 mL	1.4695 mL
	50 mM	0.0470 mL	0.2351 mL	0.4702 mL	1.1756 mL
	60 mM	0.0392 mL	0.1959 mL	0.3919 mL	0.9797 mL
	80 mM	0.0294 mL	0.1470 mL	0.2939 mL	0.7348 mL
	100 mM	0.0235 mL	0.1176 mL	0.2351 mL	0.5878 mL