FMJ-01-042
FMJ-01-042 is a blood-brain barrier-permeable, low-efficacy partial agonist with high affinity (Kᵢ = 4.33 nM) and exceptional subtype selectivity for the dopamine D4 receptor. FMJ-01-042 exhibits good metabolic stability and is suitable for research on neurological and psychiatric disorders.
For research use only. We do not sell to patients.
- Formula: C24H25N5
- Molecular Weight:383.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
FMJ-01-042 (Compound 18) (90 min) can act as a D4R-mediated β-arrestin recruitment antagonist[1].
FMJ-01-042 exhibited good metabolic stability in rat liver microsomes, with a t1/2 value of 56.77 min[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 383.49
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Formula C24H25N5
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SMILES
CC1=CC(N2N=NC(CN3CCN(C4=C5C=CC=CC5=CC=C4)CC3)=C2)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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