Forazapadin
Forazapadin (Forazapadinum) is a AAK1 inhibitor that inhibits AAK1, BIKE, and GAK. Forazapadin can be used in research related to AAK1-mediated diseases and muscle disorders.
For research use only. We do not sell to patients.
- CAS No.: 3061827-86-6
- Formula: C24H27N7O4
- Molecular Weight:477.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Forazapadin (I-34) exhibits potent in vitro biochemical inhibitory activity against AAK1 (AAK1 pSEN EIC50 = 1-50 nM), and moderately inhibits intracellular AAK1 as detected by Western blotting (intracellular AAK1 IC50 = 151-500 nM). It shows moderate inhibitory activity against BIKE (BIKE pSEN IC50 = 151-500 nM), extremely weak inhibitory activity against GAK (GAK pSEN IC50 > 1500 nM), and displays optimal targeting preference for AAK1 over GAK[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3061827-86-6
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Molecular Weight 477.52
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Formula C24H27N7O4
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SMILES
O=C(N(C1)C)C[C@@H]1OC(N(CC2)CCN2C3=NC(N(C=C3)N=C4)=C4C(C=CC=N5)=C5OC6CC6)=O
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Synonyms
Forazapadinum
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Forazapadin Related Classifications
HY-184096 Related Classifications
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