FPR2 agonist 6
FPR2 agonist 6 is an FPR1 agonist with an EC50 of 3.2 μM. FPR2 agonist 6 activates FPR1, inducing calcium mobilization and chemotaxis in human neutrophils without activating related FPR-like subtypes.
For research use only. We do not sell to patients.
- CAS No.: 1184304-45-7
- Formula: C22H22BrN3O3
- Molecular Weight:456.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
FPR1 3.2 μM (EC50) |
In Vitro
FPR2 agonist 6 induces Ca2+ mobilization in human neutrophils with an EC50 of 0.8 μM[1].
FPR2 agonist 6 is a potent chemotactic agonist of human neutrophils, with an EC50 of 0.6 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1184304-45-7
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Molecular Weight 456.33
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Formula C22H22BrN3O3
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SMILES
O=C1C(CC2=CC(OC)=CC=C2)=CC(C)=NN1C(C)C(NC3=CC=C(C=C3)Br)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)