6-TAMRA
Based on 1 publication(s) in Google Scholar
6-TAMRA (6-Carboxytetramethylrhodamine) is a fluorescent dye. 6-TAMRA is often used in combination with 6-FAM (HY-66021) as an acceptor or fluorescence quencher for fluorescence resonance energy transfer (FRET) in biochemical studies such as potassium ion detection and ribonuclease activity assays.
For research use only. We do not sell to patients.
- Purity: 98.78%
- CAS No.: 91809-67-5
- Formula: C25H22N2O5
- Molecular Weight:430.45
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 6-TAMRA
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Biological Activity
6-TAMRA, in the form of succinimidyl ester, undergoes conjugation with 3'-amino-modified oligonucleotides via incubation at 37℃ for 12 h in a pH 8.5 sodium bicarbonate buffer, and is further used as a 3'-end labeling dye for fluorescence quenching[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 91809-67-5
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Appearance Solid
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Molecular Weight 430.45
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Formula C25H22N2O5
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Color Brown to black
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SMILES
CN(C1=CC2=[O+]C3=C(C=CC(N(C)C)=C3)C(C4=CC(C([O-])=O)=CC=C4C(O)=O)=C2C=C1)C
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Synonyms
6-Carboxytetramethylrhodamine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Control Release
Albumin binding revitalizes NQO1 bioactivatable drugs as novel therapeutics for pancreatic cancer. [Abstract]2022 Aug 4;349:876-889. PMID: 35907592
Solvent & Solubility
DMSO : 2.86 mg/mL (6.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Ueyama H, et al. A novel potassium sensing in aqueous media with a synthetic oligonucleotide derivative. Fluorescence resonance energy transfer associated with Guanine quartet-potassium ion complex formation. J Am Chem Soc. 2002;124(48):14286-14287. [Content Brief]
[2]. Kelemen BR, et al. Hypersensitive substrate for ribonucleases. Nucleic Acids Res. 1999;27(18):3696-3701. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3232 mL | 11.6158 mL | 23.2315 mL | 58.0788 mL |
| 5 mM | 0.4646 mL | 2.3232 mL | 4.6463 mL | 11.6158 mL |
6-TAMRA Related Classifications
HY-15943 Related Classifications
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