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Cat. No.: HY-123251

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DB-766

DB-766 is an anti-parasite and antileishmanial agent, and is active against T. cruzi. DB-766 effectively reduces the parasite load in the blood and cardiac tissue.

For research use only. We do not sell to patients.

CAS No.: 423165-22-4
Formula: C₃₄H₃₄N₆O₃
Molecular Weight:574.67

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

DB-766 Chemical Structure

CAS No.: 423165-22-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

DB-766 is an anti-parasite and antileishmanial agent, and is active against T. cruzi. DB-766 effectively reduces the parasite load in the blood and cardiac tissue^[1].

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
L6	IC₅₀	3 μM Compound: DB766	Cytotoxicity against rat L6 cells after 3 days by Alamar blue assay Cytotoxicity against rat L6 cells after 3 days by Alamar blue assay	[PMID: 24956553]
L6	IC₅₀	3 μM Compound: DB766	Cytotoxicity against rat L6 cells Cytotoxicity against rat L6 cells	[PMID: 22840696]

Chemical Information

CAS No. 423165-22-4
Molecular Weight 574.67
Formula C₃₄H₃₄N₆O₃
SMILES

CC(C)OC1=CC(NC(C2=NC=CC=C2)=N)=CC=C1C3=CC=C(O3)C4=CC=C(C=C4OC(C)C)NC(C5=NC=CC=C5)=N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Batista Dda G, et al. Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment. Antimicrob Agents Chemother. 2010 Jul;54(7):2940-52. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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DB-766

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

DB-766 Related Classifications

HY-123251 Related Classifications