CP320626
CP320626 is a potent inhibitor of human liver glycogen phosphorylase (IC50=205 nM). CP320626 reduces blood glucose in diabetic mice without changing plasma insulin levels. CP320626 can be used in the study of type 2 diabetes.
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- CAS No.: 186430-23-9
- Formule: C23H23ClFN3O3
- Masse moléculaire:443.90
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
1.7 μM
Compound: CP-320626
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Inhibition of glucagon-induced glycogenolysis in Sprague-Dawley rat hepatocytes
Inhibition of glucagon-induced glycogenolysis in Sprague-Dawley rat hepatocytes
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[PMID: 18434170] |
| Hepatocyte | IC50 |
1.7 μM
Compound: CP-320626
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Inhibition of glucagon-induced glucose output in cultured rat primary hepatocytes
Inhibition of glucagon-induced glucose output in cultured rat primary hepatocytes
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[PMID: 18952447] |
Chemical Information
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CAS No. 186430-23-9
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Masse moléculaire 443.90
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Formule C23H23ClFN3O3
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SMILES
O=C(C(N1)=CC2=C1C=CC(Cl)=C2)N[C@@H](CC3=CC=C(F)C=C3)C(N4CCC(O)CC4)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP320626 Related Classifications
HY-117172 Related Classifications
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