Furosemide-d5
Based on 1 Customer Validation
Furosemide-d5 is the deuterated-labeled Furosemide (HY-B0135). Furosemide is an orally active GABAA receptor antagonist. Furosemide inhibits carbonic anhydrase, the sodium-chloride cotransporter, sodium reabsorption, tubuloglomerular feedback, and GABA-induced chloride flux. Furosemide can be used as a diuretic reagent. Furosemide is applied in the research of hepatic necrosis, sepsis-associated acute kidney injury, hypoalbuminemia-related fluid retention, and congestive heart failure.
For research use only. We do not sell to patients.
- Purity : 99.85%
- CAS No.: 1189482-35-6
- Formula: C12H6D5ClN2O5S
- Molecular Weight:335.77
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1189482-35-6
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Unlabeled CAS 54-31-9
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Appearance Solid
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Molecular Weight 335.77
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Formula C12H6D5ClN2O5S
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Color White to off-white
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SMILES
OC(C1=C(C=C(C(S(N)(=O)=O)=C1)Cl)NC([2H])([2H])C2=C([2H])C([2H])=C([2H])O2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (297.82 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (291 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9782 mL | 14.8911 mL | 29.7823 mL | 74.4557 mL |
| 5 mM | 0.5956 mL | 2.9782 mL | 5.9565 mL | 14.8911 mL | |
| 10 mM | 0.2978 mL | 1.4891 mL | 2.9782 mL | 7.4456 mL | |
| 15 mM | 0.1985 mL | 0.9927 mL | 1.9855 mL | 4.9637 mL | |
| 20 mM | 0.1489 mL | 0.7446 mL | 1.4891 mL | 3.7228 mL | |
| 25 mM | 0.1191 mL | 0.5956 mL | 1.1913 mL | 2.9782 mL | |
| 30 mM | 0.0993 mL | 0.4964 mL | 0.9927 mL | 2.4819 mL | |
| 40 mM | 0.0745 mL | 0.3723 mL | 0.7446 mL | 1.8614 mL | |
| 50 mM | 0.0596 mL | 0.2978 mL | 0.5956 mL | 1.4891 mL | |
| 60 mM | 0.0496 mL | 0.2482 mL | 0.4964 mL | 1.2409 mL | |
| 80 mM | 0.0372 mL | 0.1861 mL | 0.3723 mL | 0.9307 mL | |
| 100 mM | 0.0298 mL | 0.1489 mL | 0.2978 mL | 0.7446 mL |
Furosemide-d5 Related Classifications
HY-B0135S Related Classifications
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