Galectin-3-IN-5
Galectin-3-IN-5 (Compound 20) is an orally active inhibitor of galectin-3 (Gal-3), with an IC50 value of 9.2 nM against hGal-3.
For research use only. We do not sell to patients.
- Formula: C24H19BrClF5N6O4S
- Molecular Weight:697.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Galectin Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
hGal-3 9.2 nM (IC50) |
hGal-1 2400 nM (IC50) |
hGal-9 7200-7300 nM (IC50) |
mGal-3 40-57 nM (IC50) |
Chemical Information
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Molecular Weight 697.86
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Formula C24H19BrClF5N6O4S
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SMILES
CN1N=C(N(C2=C(C(F)(F)F)C=CC(Cl)=C2)C1=S)[C@@H]3O[C@@H]([C@@H]([C@H](N4C=C(C5=C(C(F)=C(C=C5)Br)F)N=N4)[C@H]3O)O)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)