2. GPCR/G Protein
  3. GnRH Receptor
  4. Ganirelix

Ganirelix is a competitive and selective gonadotropin releasing hormone (GnRH) antagonist. Ganirelix prevents endogenous GnRH from inducing luteinising hormone (LH) and follicle stimulating hormone relea.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ganirelix Chemical Structure

Ganirelix Chemical Structure

CAS No. : 124904-93-4

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Ganirelix Related Antibodies

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Description

Ganirelix is a competitive and selective gonadotropin releasing hormone (GnRH) antagonist. Ganirelix prevents endogenous GnRH from inducing luteinising hormone (LH) and follicle stimulating hormone relea[1].

In Vivo

Ganirelix (0.1 mg/kg; s.c.; daily for 14 d) reduces luteinising hormone levels in female rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Sprague-Dawley rats, weighing 225–300 mg[2]
Dosage: 0.1 mg/kg
Administration: Subcutaneous injection, daily for 14 d
Result: Reduced luteinising hormone levels.
Clinical Trial
Molecular Weight

1570.32

Formula

C80H113ClN18O13
CAS No.
Sequence

Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-{Har(Et,Et)}-Leu-{Har(Et,Et)}-Pro-D-Ala-NH2
Sequence Shortening

Ac-{D-2Nal}-{D-Phe(4-Cl)}-{D-3Pal}-SY-{D-Har(Et,Et)}-L-{Har(Et,Et)}-P-{D-Ala}-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ganirelix Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganirelix124904-93-4GnRH ReceptorGonadotropin releasing hormone receptorGNRHRluteinising hormoneLHgonadotropin releasing hormonehormone releaInhibitorinhibitorinhibit

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HY-P1628
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