DP00477
Based on 1 Customer Validation
DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer.
For research use only. We do not sell to patients.
- Purity: 98.21%
- CAS No.: 169120-56-3
- Formula: C17H11ClF3N3OS
- Molecular Weight:397.80
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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IDO1 7.0 μM (IC50) |
Chemical Information
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CAS No. 169120-56-3
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Appearance Solid
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Molecular Weight 397.80
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Formula C17H11ClF3N3OS
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Color White to light yellow
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SMILES
O=C(NC1=CC=CC(C(F)(F)F)=C1)C(C#N)C(NC2=CC=CC=C2Cl)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (251.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5138 mL | 12.5691 mL | 25.1383 mL | 62.8457 mL |
| 5 mM | 0.5028 mL | 2.5138 mL | 5.0277 mL | 12.5691 mL | |
| 10 mM | 0.2514 mL | 1.2569 mL | 2.5138 mL | 6.2846 mL | |
| 15 mM | 0.1676 mL | 0.8379 mL | 1.6759 mL | 4.1897 mL | |
| 20 mM | 0.1257 mL | 0.6285 mL | 1.2569 mL | 3.1423 mL | |
| 25 mM | 0.1006 mL | 0.5028 mL | 1.0055 mL | 2.5138 mL | |
| 30 mM | 0.0838 mL | 0.4190 mL | 0.8379 mL | 2.0949 mL | |
| 40 mM | 0.0628 mL | 0.3142 mL | 0.6285 mL | 1.5711 mL | |
| 50 mM | 0.0503 mL | 0.2514 mL | 0.5028 mL | 1.2569 mL | |
| 60 mM | 0.0419 mL | 0.2095 mL | 0.4190 mL | 1.0474 mL | |
| 80 mM | 0.0314 mL | 0.1571 mL | 0.3142 mL | 0.7856 mL | |
| 100 mM | 0.0251 mL | 0.1257 mL | 0.2514 mL | 0.6285 mL |