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Lycorenine

Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities.

For research use only. We do not sell to patients.

CAS No.: 477-19-0
Formula: C₁₈H₂₃NO₄
Molecular Weight:317.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Lycorenine Chemical Structure

CAS No.: 477-19-0

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Sample (0.1mg)

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities^[1]^[2]^[3].

In Vitro

Lycorenine inhibits the cell viability, with IC₅₀s of 0.8 and 1.2 μg/mL for LMTK and HEPG2 cells, respectively^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Lycorenine (1-10 mg/kg i.v.) produces dose-related decreases in blood pressure and heart rate in anesthetized rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 477-19-0
Molecular Weight 317.38
Formula C₁₈H₂₃NO₄
SMILES

CN1[C@@]2([H])[C@]3([H])C4=CC(OC)=C(OC)C=C4[C@H](O[C@]3([H])CC=C2CC1)O
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
- Plants
- other families
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Miyasaka K, et, al. Pharmacological studies of lycorenine, an alkaloid of Lycoris radiata Herb.: Vasodepressor mechanism in rats. Jpn J Pharmacol. 1979 Aug;29(4):605-22. [Content Brief]

[2]. Weniger B, et, al. Cytotoxic activity of Amaryllidaceae alkaloids. Planta Med. 1995 Feb;61(1):77-9. [Content Brief]

[3]. Gu D, et, al. Antibacterial Phytosterols and Alkaloids from Lycoris radiate. Natural Product Sciences. 2014 Jou; 20(2): 107-112.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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