5-PT
Based on 1 publication(s) in Google Scholar
5-PT (5-Propargyltryptamide) is an alkyne-functionalized 5-HT (HY-B1473A) derivative and serotonylation substrate, taken up by living cells. 5-PT conjugated to a biotin enables identification of serotonylated proteins via copper-click chemistry and mass spectrometry. 5-PT labels and isolates serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT can be used for the research of bronchopulmonary dysplasia.
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- No. CAS: 92085-05-7
- Fòrmula: C13H14N2O
- Peso molecular:214.26
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) 5-PT
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Actividad biológica
5-PT (100 μM; 24 h) treatment of MLE-12 alveolar epithelial cells labels 121 unique serotonylated proteins, many of which are associated with cellular processes and cell behavior regulation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 92085-05-7
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Peso molecular 214.26
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Fòrmula C13H14N2O
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SMILES
NCCC1=CNC2=C1C=C(OCC#C)C=C2
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Synonyms
5-Propargyltryptamide
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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iScience
2025 Nov 19;28(12):114120. PMID: 41438086
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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