7-Hydroxy-DPAT hydrobromide
Based on 1 Customer Validation
7-Hydroxy-DPAT hydrobromide is a selective D3 dopamine receptor agonist, exhibiting significant pharmacological activity in modulating locomotor behavior and dopamine metabolism within the brain.
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- Pureza: 99.84%
- No. CAS: 76135-30-3
- Fòrmula: C16H26BrNO
- Peso molecular:328.29
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Almacenamiento:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Ver todos los productos específicos de isoformas Dopamine Receptor
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U2OS | EC50 |
0.95 nM
Compound: 7-OH-DPA
|
Agonist activity at dopamine D3 receptor in human U2OS-D3 cells assessed as EA-tagged beta-arrestin translocation after 1.5 hrs by luminescence based beta-galactosidase assay
Agonist activity at dopamine D3 receptor in human U2OS-D3 cells assessed as EA-tagged beta-arrestin translocation after 1.5 hrs by luminescence based beta-galactosidase assay
|
[PMID: 23018094] |
Chemical Information
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No. CAS 76135-30-3
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Appearance Solid
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Peso molecular 328.29
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Fòrmula C16H26BrNO
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Color White to off-white
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SMILES
OC1=CC=C2CCC(N(CCC)CCC)CC2=C1.Br
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
DMSO : 50 mg/mL (152.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0461 mL | 15.2304 mL | 30.4609 mL | 76.1522 mL |
| 5 mM | 0.6092 mL | 3.0461 mL | 6.0922 mL | 15.2304 mL | |
| 10 mM | 0.3046 mL | 1.5230 mL | 3.0461 mL | 7.6152 mL | |
| 15 mM | 0.2031 mL | 1.0154 mL | 2.0307 mL | 5.0768 mL | |
| 20 mM | 0.1523 mL | 0.7615 mL | 1.5230 mL | 3.8076 mL | |
| 25 mM | 0.1218 mL | 0.6092 mL | 1.2184 mL | 3.0461 mL | |
| 30 mM | 0.1015 mL | 0.5077 mL | 1.0154 mL | 2.5384 mL | |
| 40 mM | 0.0762 mL | 0.3808 mL | 0.7615 mL | 1.9038 mL | |
| 50 mM | 0.0609 mL | 0.3046 mL | 0.6092 mL | 1.5230 mL | |
| 60 mM | 0.0508 mL | 0.2538 mL | 0.5077 mL | 1.2692 mL | |
| 80 mM | 0.0381 mL | 0.1904 mL | 0.3808 mL | 0.9519 mL | |
| 100 mM | 0.0305 mL | 0.1523 mL | 0.3046 mL | 0.7615 mL |